Description

Allergies
Grape seeds are a rich source of bioflavonoids known as proanthocyanidins. These powerful antioxidants are effective in the treatment of many problems. The proanthocyanidins found in grape seeds are called leucoanthocyanins. They have been shown in vitro to prevent the synthesis and release of histamine, prostaglandins, and leukotrienes. Moreover, the antioxidant effect of grape seed extract is believed to be beneficial to allergy sufferers. Oxidation is a vital process in the body, but too much oxidation can exacerbate inflammation and the allergic response. Bioflavonoid-source antioxidants are thought to be particularly helpful in supporting the immune system and combating oxidation.

Circulatory Health
Leucoanthocyanins appear to have a strengthening effect on collagen, which is vital to the integrity of the body's connective tissues. This may be beneficial to individuals with circulatory disorders by fortifying the tone and elasticity of blood vessels. In one trial, grape seed leucoanthocyanins were given to patients suffering from peripheral vascular disease of the lower limbs. Symptoms such as hemorrhaging, ruptures, and infection were reduced.

Skin Health
The same collagen-strengthening effect may support skin tone as we age, and leucoanthocyanins may also provide some protection against skin damage caused by exposure to ultraviolet rays.

Scientific Background
Allergies are a malfunction of the immune system. The immune system is an intricate network of checks and balances designed to detect antigens, which are harmful invaders, such as bacteria and viruses. It does this by releasing several substances within the body, such as histamine, prostaglandins, and leukotrienes. These substances trigger inflammatory reactions such as sneezing, coughing, and swelling, which are meant to push the invaders out of the body. Allergies occur when the immune system identifies a harmless, everyday substance, such as dust or pollen, as an invader, and attempts to expel it as it would other antigens. One common means of quelling this reaction is to take antihistamines, which effectively disarm histamine. However, over time the body can become accustomed to antihistamines and require higher dosages or more powerful drugs, with accompanying adverse effects. Some allergy sufferers are turning to natural remedies that support the immune system and prevent the release of histamine and other inflammatory substances. Many of these remedies are without adverse effects and the body does not build up a tolerance to them.